VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Mouse

Scientific Name: Mus musculus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae-> Mus-> Mus

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Ebola virus

Family: Filoviridae

Receptor: CLEC4G

Receptor CLEC4G information

Summary: This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_110001 2018.02 Microwell-seq Bladder Normal 2746 Link
Vthunter_110002 2018.02 Microwell-seq BoneMarrow Normal 510 Link
Vthunter_110004 2018.02 Microwell-seq BoneMarrowcKit Normal 13019 Link
Vthunter_110005 2018.02 Microwell-seq BoneMarrowcKit Normal 8166 Link
Vthunter_110006 2018.02 Microwell-seq Brain Normal 3285 Link
Vthunter_110008 2018.02 Microwell-seq EmbryonicMesenchymeE14.5 Normal 2771 Link
Vthunter_110013 2018.02 Microwell-seq Fetal MaleGonad Normal 3472 Link
Vthunter_110014 2018.02 Microwell-seq Fetal Stomach Normal 6192 Link
Vthunter_110015 2018.02 Microwell-seq Kidney Normal 4682 Link
Vthunter_110016 2018.02 Microwell-seq Liver Normal 4424 Link
Vthunter_110017 2018.02 Microwell-seq Liver Normal 261 Link
Vthunter_110018 2018.02 Microwell-seq Lung Normal 2512 Link
Vthunter_110019 2018.02 Microwell-seq Lung Normal 1414 Link
Vthunter_110020 2018.02 Microwell-seq Lung Normal 3014 Link
Vthunter_110021 2018.02 Microwell-seq MammaryGland.Involution Normal 3510 Link
Vthunter_110022 2018.02 Microwell-seq MammaryGland.Involution Normal 1311 Link
Vthunter_110024 2018.02 Microwell-seq MammaryGland.Lactation Normal 6905 Link
Vthunter_110025 2018.02 Microwell-seq MammaryGland.Pregnancy Normal 4909 Link
Vthunter_110026 2018.02 Microwell-seq MammaryGland.Virgin Normal 2081 Link
Vthunter_110027 2018.02 Microwell-seq MammaryGland.Virgin Normal 1059 Link
Vthunter_110028 2018.02 Microwell-seq MammaryGland.Virgin Normal 648 Link
Vthunter_110031 2018.02 Microwell-seq MesenchymalStemCellsPrimary Normal 7319 Link
Vthunter_110033 2018.02 Microwell-seq Muscle Normal 1102 Link
Vthunter_110036 2018.02 Microwell-seq NeonatalHeart Normal 3948 Link
Vthunter_110039 2018.02 Microwell-seq NeonatalPancreas Normal 4571 Link
Vthunter_110043 2018.02 Microwell-seq NeonatalSkin Normal 3392 Link
Vthunter_110044 2018.02 Microwell-seq Ovary Normal 1931 Link
Vthunter_110045 2018.02 Microwell-seq Pancreas Normal 3610 Link
Vthunter_110046 2018.02 Microwell-seq PeripheralBlood Normal 3201 Link
Vthunter_110047 2018.02 Microwell-seq PlacentaE14.1 Normal 1873 Link
Vthunter_110048 2018.02 Microwell-seq PlacentaE14.2 Normal 2473 Link
Vthunter_110052 2018.02 Microwell-seq SmallIntestine Normal 1671 Link
Vthunter_110054 2018.02 Microwell-seq Spleen Normal 1970 Link
Vthunter_110056 2018.02 Microwell-seq Testis Normal 2216 Link
Vthunter_110057 2018.02 Microwell-seq Testis Normal 11789 Link
Vthunter_110058 2018.02 Microwell-seq TrophoblastStemCells Normal 19489 Link
Vthunter_110066 2019.12 MARS-seq TotalBrain Normal 2304 Link
Vthunter_110101 2020.09 10X Genomics Teeth Teeth 2888 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CLEC4G in human tissues   [NCBI]

Expression: Biased expression in liver (RPKM 17.2), lymph node (RPKM 6.5) and 4 other tissues

Protein expression of CLEC4G in human tissues   [Proteinatlas]